Distinct Sets of Genetic Alterations in Melanoma

ABSTRACT: We compared genome-wide DNA copy number alterations and mutational status in BRAF and RAS genes of 126 primary melanomas arising in four groups in which UV exposure differ: skin with (n=30), and without chronic sun damage (n=40); palms, soles and subungual (acral) sites (n=36) (which have very little sun exposure); and mucosa (n=20) (no sun exposure).

ORGANISM(S): Homo sapiens

SUBMITTER: P LeBoit 

PROVIDER: E-GEOD-2631 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress