Expression data from human amnion mesenchymal cells treated with interleukin-1-beta for 1hr and 8hr

ABSTRACT: Premature birth continues to be a challenging pregnancy complication, and a body of literature indicates that inflammation can contribute to premature delivery by converting a receptive uterine environment to a hostile one. Cytokines have been demonstrated to provoke up-regulation of inflammatory genes (e.g. interleukin-1, 6, and 8, tumor necrosis factor-alpha, cyclooxygenase-2, and microsomal prostaglandin E synthase-1). Using monolayer cultures of human amnion mesenchymal cells (AMCs) as a model, we aimed to detail the global programme of gene expression that occurs in response to cytokine challenge. Human amnion mesenchymal cells were challenged with 10 ng/ml of interleukin-1-beta for 1 hour (1h) or 8 hours (8h) in serum-free media, while control cells were treated with serum free medi

ORGANISM(S): Homo sapiens

SUBMITTER: Douglas Kniss 

PROVIDER: E-GEOD-26315 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress