Genome-Wide Microarray Analysis of Gene Expression During Starvation in Tetrahymena thermophila

ABSTRACT: Two genome-wide microarrays containing the predicted coding sequences (putative genes) for the ciliated protozoan Tetrahymena thermophila were used to study gene expression in starved cells (starvation 0 hour and starvation 24 hour). Combining these two microarrays with 50 microarrays described in Miao et al. (2009) and 15 other microarrays, we constructed the Tetrahymena gene network (TGN) using three methods: the Pearson correlation coefficient, the Spearman correlation coefficient and the context likelihood of relatedness (CLR) algorithm. The accuracy and coverage of the three networks were evaluated using four conserved protein complexes in yeast, and the CLR network was found to be the best network, with a Z-score threshold 3.49. Then the TGN was partitioned, and 55 modules were found

ORGANISM(S): Tetrahymena thermophila

SUBMITTER: Wei Miao 

PROVIDER: E-GEOD-26384 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress