Gene expression data from treated LNCaP prostate cells.

ABSTRACT: Prostate cancer is dependent on androgen receptor (AR) signaling at all stages of the disease and cyclin D1 has been shown to negatively modulate the expression of the AR-dependent gene prostate specific antigen (KLK3/PSA). Unbiased gene expression profiling was performed to determine the androgen-regulated geneset that is sensitive to cyclin D1. Androgen-sensitive LNCaP cells were straved of androgen, then transduced with control green fluorescent protein (GFP) or cyclin D1 (CCND1) adenovirus, then subsequently stimulated with control (Ethanol) or dihydrotestosterone (DHT).

ORGANISM(S): Homo sapiens

SUBMITTER: Clay Comstock 

PROVIDER: E-GEOD-26483 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress