Expression data from human fibroblasts 6 and 12 hours after 8-oxoguanine treatment

ABSTRACT: 8-oxoguanine is excised from DNA by 8-oxoguanine DNA glycosylase-1 during DNA base excision repair. We used microarrays to gain insight into the potential biological function of the excised, free 8-oxoguanine base. MRC5, human diploid fibroblasts were exposed to 8-oxoguanine and changes in gene expression compared to mock control were analyzed 6 hours after exposure. MRC5, human diploid fibroblasts were exposed to 8-oxoguanine and changes in gene expression compared to mock control were analyzed 12 hours after exposure.

ORGANISM(S): Homo sapiens

SUBMITTER: Istvan Boldogh 

PROVIDER: E-GEOD-26813 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress