Stromal molecular signatures of breast and prostate cancer

ABSTRACT: Primary tumor growth induces host tissue responses that are believed to support and promote tumor progression. Identification of the molecular characteristics of the tumor microenvironment and elucidation of its crosstalk with tumor cells may therefore be crucial for improving our understanding of the processes implicated in cancer progression, identifying potential therapeutic targets, and uncovering stromal gene expression signatures that may predict clinical outcome. A key issue to resolve, therefore, is whether the stromal response to tumor growth is largely a generic phenomenon, irrespective of the tumor type, or whether the response reflects tumor-specific properties. To address similarity or distinction of stromal gene expression changes during cancer progression, oligonucleotide-ba

ORGANISM(S): Homo sapiens

SUBMITTER: Paolo Provero 

PROVIDER: E-GEOD-26910 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress