Ontology highlight
ABSTRACT:
ORGANISM(S): Caulobacter crescentus NA1000
SUBMITTER: Rogerio Lourenco
PROVIDER: E-GEOD-26977 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Lourenço Rogério F RF Kohler Christian C Gomes Suely L SL
Molecular microbiology 20110512 6
The extracytoplasmic function sigma factor σ(T) is the master regulator of general stress response in Caulobacter crescentus and controls the expression of its paralogue σ(U). In this work we showed that PhyR and NepR act, respectively, as positive and negative regulators of σ(T) expression and function. Biochemical data also demonstrated that NepR directly binds σ(T) and the phosphorylated form of PhyR. We also described the essential role of the histidine kinase gene CC3474, here denominated p ...[more]