Cx expression profiling
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Suzanne Vernon
PROVIDER: E-GEOD-2711 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Gene expression profile of cervical tissue compared to exfoliated cells: impact on biomarker discovery.
Steinau Martin M Lee Daisy R DR Rajeevan Mangalathu S MS Vernon Suzanne D SD Ruffin Mack T MT Unger Elizabeth R ER
BMC genomics 20050505
<h4>Background</h4>Exfoliated cervical cells are used in cytology-based cancer screening and may also be a source for molecular biomarkers indicative of neoplastic changes in the underlying tissue. However, because of keratinization and terminal differentiation it is not clear that these cells have an mRNA profile representative of cervical tissue, and that the profile can distinguish the lesions targeted for early detection.<h4>Results</h4>We used whole genome microarrays (25,353 unique genes) ...[more]
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