Comparative genomic hybridization of strains of Leishmania infantum, Leishmania major and Leishmania tarentolae

ABSTRACT: The genomic DNAs of strains JPCM5 and 263 of L. infantum, strains LV39 and Friedlin of L. major and strains Parrot-TarII and S125 of L. tarentolae were used in comparative genomic hybridizations to reveal the intra-species and inter-species gene content, and to validate L. tarentolae Parrot-TarII genome sequencing results. Leishmania (Sauroleishmania) tarentolae was first isolated in the lizard Tarentola mauritanica. This species is not known to be pathogenic to humans but is often used as a model organism for molecular analyses or protein overproduction. The Leishmania tarentolae Parrot-TarII strain genome sequence was resolved by high-throughput sequencing technologies. The L. tarentolae genome was first assembled de novo and then aligned against the reference L. major Friedlin genome to

ORGANISM(S): Leishmania tarentolae

SUBMITTER: Frederic Raymond 

PROVIDER: E-GEOD-27184 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress