Transcriptome changes at the initiation of elongation in the bovine conceptus

ABSTRACT: Temporal changes in the embryo transcriptome between the blastocyst stage (Day 7) and initiation of elongation (Day 13) differ between in vivo- and in vitro-derived embryos and are reflective of subsequent developmental fate. The aim of this study was to examine the temporal changes in transcriptional profile as the embryo develops from a spherical blastocyst on Day 7 to an ovoid conceptus at the initiation of elongation on Day 13 and to highlight differences in these temporal gene expression dynamics between in vivo- and in vitro-derived blastocysts which may be associated with embryonic survival/mortality using the bovine Affymetrix microarray. All embryos were produced either in vitro by IVF or in vivo by superovulation. A proportion of Day 7 blastocysts were snap frozen and the remaind

ORGANISM(S): Bos taurus

SUBMITTER: Jai Prakash Mehta 

PROVIDER: E-GEOD-27817 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress