Post-fasting olfactory, transcriptional, and feeding responses in Drosophila

ABSTRACT: The sensation of hunger after a period of fasting and the sensation of satiety after eating is crucial to behavioral regulation of food intake, but the biological mechanisms regulating these sensations are incompletely understood. We studied the behavioral and physiological adaptation to fasting in the vinegar fly (Drosophila melanogaster). Here we show that flies demonstrated increased behavioral attraction to food odor when food-deprived with no corresponding increase in sensitivity in the peripheral olfactory system. Flies increased their food intake transiently in the post-fasted state, but returned to a stable baseline feeding level within 24 hr after return to food. This modulation in feeding was accompanied by a significant increase in the size of the crop organ of the digestive sys

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Mayte Suarez-Farinas 

PROVIDER: E-GEOD-27927 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress