Dataset Information
Genome-wide CTCF binding maps in mouse ES and fibroblast cells
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: David Martin
PROVIDER: E-GEOD-27944 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes.
Nature structural & molecular biology 20110522 6
Many genomic alterations associated with human diseases localize in noncoding regulatory elements located far from the promoters they regulate, making it challenging to link noncoding mutations or risk-associated variants with target genes. The range of action of a given set of enhancers is thought to be defined by insulator elements bound by the 11 zinc-finger nuclear factor CCCTC-binding protein (CTCF). Here we analyzed the genomic distribution of CTCF in various human, mouse and chicken cell ...[more]
