Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Affymetrix gene expression array data for cardia and non-cardia gastric cancer samples


ABSTRACT: We identified different and common dysregulated genes in cardia and non-cardia gastric cancer in the two type of gastric cancer cardia and non-cardia gastric tumors and normal glands

ORGANISM(S): Homo sapiens

SUBMITTER: Howard Yang 

PROVIDER: E-GEOD-29272 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Comparison of global gene expression of gastric cardia and noncardia cancers from a high-risk population in china.

Wang Gangshi G   Hu Nan N   Yang Howard H HH   Wang Lemin L   Su Hua H   Wang Chaoyu C   Clifford Robert R   Dawsey Erica M EM   Li Jian-Min JM   Ding Ti T   Han Xiao-You XY   Giffen Carol C   Goldstein Alisa M AM   Taylor Philip R PR   Lee Maxwell P MP  

PloS one 20130522 5


<h4>Objective</h4>To profile RNA expression in gastric cancer by anatomic subsites as an initial step in identifying molecular subtypes and providing targets for early detection and therapy.<h4>Methods</h4>We performed transcriptome analysis using the Affymetrix GeneChip U133A in gastric cardia adenocarcinomas (n = 62) and gastric noncardia adenocarcinomas (n = 72) and their matched normal tissues from patients in Shanxi Province, and validated selected dysregulated genes with additional RNA stu  ...[more]

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