Comprehensive analysis of miRNA expression profiles in IDA, IPMA, IPMC and cancer cell line

ABSTRACT: This study identified differentially expressed miRNAs exclusively in invasive ductal adenocarcinoma. The epithelial-mesenchymal transition (EMT) is a critical step for pancreatic cancer cells as an entry of metastatic disease. Wide variety of cytokines and signaling pathways are involved in this complex process while the entire picture is still cryptic. Recently, miRNA was found to regulate cellular function including EMT by targeting multiple mRNAs. We performed comprehensive analysis of miRNA expression profiles in invasive ductal adenocarcinoma (IDA), intraductal papillary mucinous adenoma (IPMA), intraductal papillary mucinous carcinoma (IPMC) and human pancreatic cancer cell line to elucidate essential miRNAs which regulate invasive growth of pancreatic cancer cells. Along with

ORGANISM(S): Homo sapiens

SUBMITTER: Shin Hamada 

PROVIDER: E-GEOD-29542 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress