SW13_BRG1_3arrays
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Xin Chen
PROVIDER: E-GEOD-2966 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Regulation of CSF1 promoter by the SWI/SNF-like BAF complex.
Liu R R Liu H H Chen X X Kirby M M Brown P O PO Zhao K K
Cell 20010801 3
The mammalian BAF complex regulates gene expression by modifying chromatin structure. In this report, we identify 80 genes activated and 2 genes repressed by the BAF complex in SW-13 cells. We find that prior binding of NFI/CTF to the NFI/CTF binding site in CSF1 promoter is required for the recruitment of the BAF complex and the BAF-dependent activation of the promoter. Furthermore, the activation of the CSF1 promoter requires Z-DNA-forming sequences that are converted to Z-DNA structure upon a ...[more]
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