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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Stimulation of BL2 cell line with lipopolysaccharide (LPS) for 6h

ABSTRACT: Identification of genes up or down regulated in LPS stimulated samples in comparison to control samples. 3 LPS stimulated samples vs. 3 controls were analyzed

ORGANISM(S): Homo sapiens

SUBMITTER: Matthias Maneck

PROVIDER: E-GEOD-29700 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Genomic data integration using guided clustering.

Maneck Matthias M Schrader Alexandra A Kube Dieter D Spang Rainer R

Bioinformatics (Oxford, England) 20110617 16

<h4>Motivation</h4>In biomedical research transcriptomic, proteomic or metabolomic profiles of patient samples are often combined with genomic profiles from experiments in cell lines or animal models. Integrating experimental data with patient data is still a challenging task due to the lack of tailored statistical tools.<h4>Results</h4>Here we introduce guided clustering, a new data integration strategy that combines experimental and clinical high-throughput data. Guided clustering identifies s ...[more]

PMID: 21685050

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