Dataset Information
Transcription profiling of murine R1 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: OGIC Info Ontario Genomics Innovation Centre (OGIC)
PROVIDER: E-GEOD-2972 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Gene function in early mouse embryonic stem cell differentiation.
BMC genomics 20070329
<h4>Background</h4>Little is known about the genes that drive embryonic stem cell differentiation. However, such knowledge is necessary if we are to exploit the therapeutic potential of stem cells. To uncover the genetic determinants of mouse embryonic stem cell (mESC) differentiation, we have generated and analyzed 11-point time-series of DNA microarray data for three biologically equivalent but genetically distinct mESC lines (R1, J1, and V6.5) undergoing undirected differentiation into embryo ...[more]
