Cellular Response of the bacterium Cupriavidus metallidurans CH34 to Strontium: bio-precipitation as strontium carbonate.

ABSTRACT: The physiological and transcriptomic response of the metal resistant bacterium Cupriavidus metallidurans strain CH34 in response to stable (non-radioactive) strontium ions (Sr) was investigated. C. metallidurans CH34 could survive and proliferate in the presence of relatively high concentrations of SrCl2 (D10 is 70mM, MIC is 120 mM). Precipitation of Sr as strontium carbonate was observed in the culture during aerobic growth of CH34 in the presence of 60 mM SrCl2. To identify the cellular mechanisms involved in the bioprecipitation process, gene expression in the cells was analyzed after short-time (30 min) exposure to low (5 mM) and high (60 mM) concentrations of SrCl2. The transcription of the gene clusters annotated as hmyFCBA and czcCBADRS, coding for ion efflux pumps, was significantl

ORGANISM(S): Cupriavidus metallidurans CH34

SUBMITTER: Pieter Monsieurs 

PROVIDER: E-GEOD-29863 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress