Expression data of pachytene spermatocytes and round spermatids from young and aged Brown Norway rats

ABSTRACT: Male fertility and testis function changes with age and so it was sought to determine if these changes are accompanied by changes in gene expression. A full genome microarray was used to determine if distinct pathways of genes were altered in expression in germ cells (pachytene spermatocytes or round spermatids) with age. PACH: Testes from young (4 months) and aged (18 months) Brown Norway rats were subjected to a density gradient cell separation to isolate pachytene spermatocytes. RNA was isolated from these cells for hybridization on affymetrix miroarrays. ROU: Testes from young (4 months) and aged (18 months) Brown Norway rats were subjected to a density gradient cell separation to isolate round spermatids. RNA was isolated from these cells for hybridization on affymetrix miroarrays.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Bernard Robaire 

PROVIDER: E-GEOD-29963 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress