Transcriptomic analysis of porcine muscle Biceps femoris (BF) exposed to a single bout of endurance exercise

ABSTRACT: Acute physical exercise elicits changes in gene expression in skeletal muscles to promote metabolic changes and to repair exercise-induced muscle injuries. Here, we investigated the impact of a single bout of running exercise until exhaustion on global transcriptional profiles in porcine skeletal muscles. Using a combined microarray and candidate gene approach, we identified a suite of genes that are differentially expressed in muscles during post-exercise recovery. Thus, several members of the heat shock protein family and proteins associated with proteolytic events were significantly up-regulated, suggesting that protein breakdown, prevention of protein aggregation and stabilization of unfolded proteins are important processes for restoring cellular homeostasis. We also detected an up-re

ORGANISM(S): Sus scrofa

SUBMITTER: Lene Conley 

PROVIDER: E-GEOD-30013 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress