A new classification of chromosome instability (CIN) phenotype, CIN-high and CIN-low

ABSTRACT: Samples were taken from colorectal cancers in surgically resected specimens in 35 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be used for molecular markers for CIN phynotype. Specimens from 35 consecutive stage II and stage III patients who had undergone surgical resection of CRC were studied. Patients with familial adenomatous polyposis and HNPCC were excluded from the study. Specimens from tumors and corresponding normal tissues in surgically resected specimens were snap-frozen in liquid nitrogen and stored at -80 ºC until use. Parallel tumor specimens were formalin fixed and paraffin embedded for histological examinatio

ORGANISM(S): Homo sapiens

SUBMITTER: Toshiaki Watanabe 

PROVIDER: E-GEOD-30540 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress