Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Expression data from skin biopsy samples from patients with moderate-to-severe psoriasis


ABSTRACT: A gene expression profiling sub-study was conducted in which skin biopsy samples were collected from 85 patients with moderate-to-severe psoriasis who were participating in ACCEPT, an IRB-approved Phase 3, multicenter, randomized trial. This analysis identified 4,175 probe-sets as being significantly modulated in psoriasis lesions (LS) compared with matched biopsies of non-lesional (NL) skin. Skin biopsy samples (n=170) were collected at baseline for RNA extraction and microarray analysis from 85 patients with moderate-to-severe psoriasis without receiving active psoriasis therapy.

ORGANISM(S): Homo sapiens

SUBMITTER: K Li 

PROVIDER: E-GEOD-30999 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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