Effect of interleukin-1 and PDGF-DD on SMCs

ABSTRACT: This experiment tests the hypothesis that interleukin-1 promotes SMC phenotypic modulation to a distinct inflammatory state relative to the growth factor PDGF-DD. Cultured rat aortic smooth muscle cells were treated with IL-1b (2.5 ng/mL) or vehicle (0.1% BSA and 10 mM acetic acid) or PDGF-DD (30 ng/mL) or vehicle (0.01% BSA) for 24 hours prior to harvest (n=1).

ORGANISM(S): Rattus norvegicus

SUBMITTER: Gary Owens 

PROVIDER: E-GEOD-31080 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress