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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Gene expression analysis using the ureters of normal and ureteritis mice

ABSTRACT: Analysis of ureters of idiopathic ureteritis mice. The B cell functions associated genes were upregulated in the diseased ureters compared to nomal ureter. These results provide a basical information of molecular pathology in idiopathic ureteritis. In the study, the normal ureter (n=3) and diseased ureter (n=3) were used. The total RNA sample of each group was collected to 1 sample, 36,142 genes expressions were compared between these groups.

ORGANISM(S): Mus musculus

SUBMITTER: Osamu Ichii

PROVIDER: E-GEOD-31098 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression analysis using the ureters of normal and ureteritis mice

Project description:Analysis of ureters of idiopathic ureteritis mice. The B cell functions associated genes were upregulated in the diseased ureters compared to nomal ureter. These results provide a basical information of molecular pathology in idiopathic ureteritis.

2011-08-02 | GSE31098 | GEO

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2023-05-10 | PXD038161 | Pride

Experimental overactivity or blockade of transforming growth factor-B each generate a specific ureter malformation

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Analysis of embryonic day E14.5 and E16.5 mouse ureters from Tshz3LacZ/LacZ mutants and wild types

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Analysis of embryonic day E14.5 and E16.5 mouse ureters from Tshz3LacZ/LacZ mutants and wild types

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scRNA sequencing analysis for human ureters and patient derived ureter oragnoid

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Gene expression profiles of E15 ureter (GUDMAP Series ID: 26)

Project description:The long term objective is to create an encyclopedia of the expression levels of all genes in multiple components of the developing genitourinary tract. The central thesis is straightforward. The combination of microdissected tissues and FACS sorted cells plus microarray analysis offers a powerful, efficient and effective method for the creation of a global gene expression atlas of the developing urogenital system. Microarrays with essentially complete genome coverage can be used to quantitate expression levels of every gene. The ensuing rapid read-out provides an expression atlas that is more sensitive, more economical and more complete than would be possible by in situ hybridizations alone. The data submitted here delineates the gene expression profiles of the e15 mouse ureter. Comparisons with the same compartments in the neonate will be made to determine changes in gene expression from relatively undifferentiated tissue (e15) to a highly differentiated structure (neonate). FVB/N mice were time mated. At embryonic day 15 mice were euthanized by decapitation and the ureters were microdissected, cut from pelvis to the bladder insertion point and snap frozen in liquid nitrogen. Total RNA was isolated for gene expression analysis using the Affymetrix GeneChip Mouse Genome 430 2.0 Array.

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