Expression data for the different phases of ulcerative colitis-associated carcinogenesis in a mouse model

ABSTRACT: Nonresolving inflammation is correlated to carcinogenesis. Ulcerative colitis-associated colorectal cancer (UC-CRC), one of the typical carcinoma generated by inflammation that cannot be resolved properly, has been widely believed to involve a multistep process contains M-bM-^@M-^\inflammation-dysplasia-cancerM-bM-^@M-^] sequence. The exact molecular mechanisms underlying the step-wise development of UC-CRC is still not fully understood. Detecting the changes in gene expression profiles may help to reveal why and how does the prolonged inflammatory response lead to carcinogenesis, and to characterize potential diagnostic/prognostic markers or additional therapeutic targets for UC-CRC. There for, we performed temporal genome expression profiling analysis using the Affymetrix genome wide mic

ORGANISM(S): Mus musculus

SUBMITTER: tang liu 

PROVIDER: E-GEOD-31106 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress