Progestin regulation of gene expression in breast cancer and minimally transformed breast cell lines

ABSTRACT: Time course of response to synthetic progestin ORG2058 in T-47D and ZR-75-1 breast cancer cell lines and in two PR positive clones of the MCF-10A cell line: AB9 and AB32. Transcriptional response to synthetic progestin, 10nM ORG2058, was compared between the four cell lines at three treatment times. T-47D breast cancer cells were treated in triplicate with 10nM ORG2058 or ethanol vehicle and harvested at 2, 6 and 24h after treatment for gene expression profiling

ORGANISM(S): Homo sapiens

SUBMITTER: J Graham 

PROVIDER: E-GEOD-31128 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress