Molecular characterization of the chromosome 7 in SMZL
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Cristina Robledo
PROVIDER: E-GEOD-31203 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Molecular characterization of the region 7q22.1 in splenic marginal zone lymphomas.
Robledo Cristina C García Juan L JL Benito Rocío R Flores Teresa T Mollejo Manuela M Martínez-Climent José Ángel JÁ García Eva E Gutiérrez Norma C NC Piris Miguel A MA Hernández Jesús M JM
PloS one 20110921 9
Splenic marginal zone lymphomas (SMZL) are an uncommon type of B-cell non-Hodgkin's lymphoma (NHL-B) in which no specific chromosomal translocations have been described. In contrast, the most frequent cytogenetic abnormality is the loss of the long arm of chromosome 7 (7q). Previous reports have located this loss in the 7q32 region. In order to better characterize the genomic imbalances in SMZL, molecular studies were carried out in 73 patients with SMZL. To gain insight into the mapping at 7q a ...[more]
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