Identification of genes expressed in C. elegans touch receptor neurons
Ontology highlight
ABSTRACT:
ORGANISM(S): Caenorhabditis elegans
SUBMITTER: Martin Chalfie
PROVIDER: E-GEOD-3121 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Identification of genes expressed in C. elegans touch receptor neurons.
Zhang Yun Y Ma Charles C Delohery Thomas T Nasipak Brian B Foat Barrett C BC Bounoutas Alexander A Bussemaker Harmen J HJ Kim Stuart K SK Chalfie Martin M
Nature 20020701 6895
The extent of gene regulation in cell differentiation is poorly understood. We previously used saturation mutagenesis to identify 18 genes that are needed for the development and function of a single type of sensory neuron--the touch receptor neuron for gentle touch in Caenorhabditis elegans. One of these genes, mec-3, encodes a transcription factor that controls touch receptor differentiation. By culturing and isolating wild-type and mec-3 mutant cells from embryos and applying their amplified ...[more]
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