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Effect of IL-11 on gene expression in JEG-3 and HTR-8/SVneo trophoblastic cells

ABSTRACT: IL-11 increases the invasiveness of JEG-3 cells while, reduces the invasiveness of HTR-8/SVneo cells. This study examines the effect of IL-11 on gene expression in trophobalstic cell models viz. JEG-3 and HTR-8/SVneo cells to resolve the controversies associated with the IL-11 mediated regulation of the invasiveness of these two cell lines. JEG-3 and HTR-8/Svneo cells were stimulated with IL-11 (200 ng/ml) for 24 h in pain medium keeping un-treated cells as control. After 24 h of stimulation, total RNA was isolated from these cells and used for the microarray experiments. These experiments were performed once.

ORGANISM(S): Homo sapiens

SUBMITTER: Satish Gupta

PROVIDER: E-GEOD-31608 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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