Transcription profiling of mouse fibroblast cells infected with adenoviral vector or mock infected

ABSTRACT: The innate immune response to 1st generation adenoviral vectors was ascertained through high level infection of primary cells from a inbred mouse strain, replete with an intact and functioning TLR system. Experiment Overall Design: Quiescent murine C57/Bl6 fibroblasts were Ad (E1-E3-LacZ at MOI=300) or Mock infected. Sixteen hrs post-infection, RNA was harvested, transcribe to cDNA and bitotin-labeled, and hybridized to Mu11k A and B arrays.

ORGANISM(S): Mus musculus

SUBMITTER: Zachary Conrad Hartman 

PROVIDER: E-GEOD-3172 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress