Mtb-mediated host transcriptional reponse is strain-specific

ABSTRACT: CDC1551 induced more vigorous immune response in murine bone marrow derived macrophage (BMM). In contrast, in HN878-infected cells, host transcriptional response was delayed but lasted longer. HN878 induced more genes involved in host lipid metabolism than CDC1551 did. Murine bone marrow derived macrophages were infected with M. tuberculosis CDC1551 or HN878 up to 24 h. Total RNA was processed for microarray and global gene expression was read.

ORGANISM(S): Mus musculus

SUBMITTER: Mi-Sun Koo 

PROVIDER: E-GEOD-31734 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress