Response of Saccharomyces cerevisiae to a rapid transfer from a fermentable to a nonfermentable carbon source.

ABSTRACT: The global gene expression program that accompanies the adaptation of Saccharomyces cerevisiae to an abrupt transfer from a fermentable to a nonfermentable carbon source was characterized by using a cDNA microarray to monitor the relative abundances and polysomal distributions of mRNAs. Features of the program included a transient reduction in global translational activity and a severe decrease in polysome size of transcripts encoding ribosomal proteins. A replicate experimental design type is where a series of replicates are performed to evaluate reproducibility or as a pilot study to determine the appropriate number of replicates for a subsequent experiments. Using regression correlation

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Peter Sarnow 

PROVIDER: E-GEOD-3190 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress