Transcription profiling of human squamous lung cancer cells vs normal cells to identify genes that are differentially regulated
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
DISEASE(S): normal
SUBMITTER: Shinichiro Wachi
PROVIDER: E-GEOD-3268 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Interactome-transcriptome analysis reveals the high centrality of genes differentially expressed in lung cancer tissues.
Wachi Shinichiro S Yoneda Ken K Wu Reen R
Bioinformatics (Oxford, England) 20050927 23
<h4>Motivation</h4>Global protein interaction network (interactome) analysis provides an effective way to understand the relationships between genes. Through this approach, it was demonstrated that the essential genes in yeast tend to be highly connected as well as connected to other highly connected genes. This is in contrast to the genes that are not essential, which share neither of these properties. Using a similar interactome-transcriptome approach, the topological features in the interacto ...[more]
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