Comprehensive identification of long non-coding RNAs expressed during zebrafish embryogenesis [RNA_seq]

ABSTRACT: Long non-coding RNAs (lncRNAs) comprise a diverse class of transcripts that structurally resemble mRNAs but do not encode proteins. Recent genome-wide studies in human and mouse have annotated lncRNAs expressed in cell lines and adult tissues, but a systematic analysis of lncRNAs expressed during vertebrate embryogenesis has been elusive. To identify lncRNAs with potential functions in vertebrate embryogenesis, we performed a time series of RNA-Seq experiments at eight stages during early zebrafish development. We reconstructed 56,535 high-confidence transcripts in 28,912 loci, recovering the vast majority of expressed RefSeq transcripts, while identifying thousands of novel isoforms and expressed loci. We defined a stringent set of 1,133 non-coding multi-exonic transcripts expressed durin

ORGANISM(S): Danio rerio

SUBMITTER: Eivind Valen 

PROVIDER: E-GEOD-32898 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress