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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Whole genome expression profiling based on paraffin embedded tissue can be used to classify diffuse large b-cell lymphoma and predict clinical outcome

ABSTRACT: Gene expression profiling was carried out for RNA extracted from Formalin-fixed, paraffin embedded (FFPE) biopsies for 172 patients with diffuse large b-cell lymphoma (DLBCL) using the Illumina DASL platform. Classification into GCB, ABC or Type-III subtypes was carried out revealing a significant relationship between subtype and survival. A retrospective study of 172 patients, 140 treated with R-CHOP, 32 not treated with curative intent

ORGANISM(S): Homo sapiens

SUBMITTER: Matthew Care

PROVIDER: E-GEOD-32918 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Whole genome expression profiling based on paraffin embedded tissue can be used to classify diffuse large b-cell lymphoma and predict clinical outcome

Project description:Gene expression profiling was carried out for RNA extracted from Formalin-fixed, paraffin embedded (FFPE) biopsies for 172 patients with diffuse large b-cell lymphoma (DLBCL) using the Illumina DASL platform. Classification into GCB, ABC or Type-III subtypes was carried out revealing a significant relationship between subtype and survival.

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