Using DNA methylation to detect dysplasia/early neoplasia in Barrett's carcinogenesis

ABSTRACT: Dysplasia and early cancer are hard to detect in endoscopic biopsies and hence this study was carried out to evaluate the biomarker potential of DNA methylation to detect dyspasia and early cancer in Barrett's esophaghus patients. Bisulfite converted genomic DNA was hybridized onto Illumina 27k methylation arrays. 22 Barrett's esophagus (BE) and 2 Duodenum vs. 24 esophageal adenocarcinoma (EAC)

ORGANISM(S): Homo sapiens

SUBMITTER: Muhammad Alvi 

PROVIDER: E-GEOD-32925 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress