RNA polymerase inhibitor
Ontology highlight
ABSTRACT:
ORGANISM(S): Shigella flexneri
SUBMITTER: Hua Fu
PROVIDER: E-GEOD-32978 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Common changes in global gene expression induced by RNA polymerase inhibitors in Shigella flexneri.
Fu Hua H Liu Liguo L Zhang Xiaobing X Zhu Yafang Y Zhao Lina L Peng Junping J He Hongxuan H Jin Qi Q
PloS one 20120312 3
Characterization of expression profile of organisms in response to antimicrobials provides important information on the potential mechanism of action of the drugs. The special expression signature can be used to predict whether other drugs act on the same target. Here, the common response of Shigella flexneri to two inhibitors of RNA polymerase was examined using gene expression profiling. Consistent with similar effects of the two drugs, the gene expression profiles indicated that responses of ...[more]
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