MRNA-seq of L1 larvae recovering from arrest
Ontology highlight
ABSTRACT:
ORGANISM(S): Caenorhabditis elegans
SUBMITTER: Colin Maxwell
PROVIDER: E-GEOD-33023 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Nutritional control of mRNA isoform expression during developmental arrest and recovery in C. elegans.
Maxwell Colin S CS Antoshechkin Igor I Kurhanewicz Nicole N Belsky Jason A JA Baugh L Ryan LR
Genome research 20120426 10
Nutrient availability profoundly influences gene expression. Many animal genes encode multiple transcript isoforms, yet the effect of nutrient availability on transcript isoform expression has not been studied in genome-wide fashion. When Caenorhabditis elegans larvae hatch without food, they arrest development in the first larval stage (L1 arrest). Starved larvae can survive L1 arrest for weeks, but growth and post-embryonic development are rapidly initiated in response to feeding. We used RNA- ...[more]
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