Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Gene expression of Tg 3M-CM-^WFLAG-Nanos2-deltaN10 mouse male gonad


ABSTRACT: To investigate the biochemical function of NANOS2, we performed expression microarray analysis of the embyornic male gonad of Nanos2 hetero, Nanos2 KO, and Nanos2 KO_Tg 3M-CM-^WFLAG-tagged Nanos2-M-NM-^TN10, which is truncated form of Nanos2 in the N-terminal region, transgenic mice. 3M-CM-^WFLAG-tagged Nanos2-M-NM-^TN10 protein function was validated by rescue experiment in the Nanos2-null male gonad of mouse embryo at E14.5. Biological duplicates were examined at each genotype, Nanos2 hetero, Nanos2 KO, and Nanos2 KO_Tg 3M-CM-^WFLAG-tagged Nanos2-M-NM-^TN10 for each experiment.

ORGANISM(S): Mus musculus

SUBMITTER: Rie Saba 

PROVIDER: E-GEOD-33138 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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