Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Chi Ho Lin
PROVIDER: E-GEOD-33294 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Chan Tim Hon Man TH Lin Chi Ho CH Qi Lihua L Fei Jing J Li Yan Y Yong Kol Jia KJ Liu Ming M Song Yangyang Y Chow Raymond Kwok Kei RK Ng Vanessa Hui En VH Yuan Yun-Fei YF Tenen Daniel G DG Guan Xin-Yuan XY Chen Leilei L
Gut 20130613 5
<h4>Objective</h4>Hepatocellular carcinoma (HCC) is a heterogeneous tumour displaying a complex variety of genetic and epigenetic changes. In human cancers, aberrant post-transcriptional modifications, such as alternative splicing and RNA editing, may lead to tumour specific transcriptome diversity.<h4>Design</h4>By utilising large scale transcriptome sequencing of three paired HCC clinical specimens and their adjacent non-tumour (NT) tissue counterparts at depth, we discovered an average of 20 ...[more]