A functional map of DNA-associated proteolysis

ABSTRACT: We established an assay to localize DNA-associated proteins that are slated for degradation by the ubiquitin-proteasome system. The genome-wide map we describe here ties proteolysis to active enhancer elements and to transcription start sites of specific gene families. ChIP-sequencing of ubiquitin and transcription factors was performed in the presence or absence of proteasome inhibition.

ORGANISM(S): Mus musculus

SUBMITTER: Andre Catic 

PROVIDER: E-GEOD-33821 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress