Transcription profiling of human gender specific Stratagene RNA to examine dosage compensation of the active X in mammals

ABSTRACT: Here, we show that doubling of the global expression level of the X chromosome achieves dosage compensation in somatic tissues from several mammalian species. X-linked genes are highly expressed in brain tissues, consistent with a role in cognitive functions. Experiment Overall Design: Eight arrays were acquired from Affymetrix. Total gender-specific RNA was purchased from Stratagene. Probe labeling, array hybridization and scanning were done by the University of Washington Microarray Center (TUhttp://ra.microslu.washington.edu/UT). cDNA arrays.

ORGANISM(S): Homo sapiens

SUBMITTER: Di Kim Nguyen 

PROVIDER: E-GEOD-3413 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress