Determinants of excess genetic risk of acute myocardial infarction M-bM-^@M-^S a matched case-control study

ABSTRACT: Peripheral blood samples of patients with acute myocardial infarction were matched with those of control patients to identify possible differences in corresponding gene expression profiles. The controls were matched to cases based on gender, age, status of diabetes mellitus and smoking status. Six months cardiovascular survival status of the cases was used to identify two distinct subgroups among the cases. Linear models for microarray data (M-bM-^@M-^XlimmaM-bM-^@M-^Y) were employed to identify differential gene expression. Shrunken centroids technique helped in identifying the subsets of differentially expressed genes with predictive properties in independent samples. Predictive properties were evaluated using bootstrap sampling. Using the limma modeling with the log-fold change threshol

ORGANISM(S): Homo sapiens

SUBMITTER: Michal KolM-CM-!M-EM-^Y 

PROVIDER: E-GEOD-34198 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress