Only skin deep: shared genetic response to the deadly chytrid fungus in susceptible frog species

ABSTRACT: Amphibian populations around the world are threatened by an emerging infectious pathogen, the chytrid fungus Batrachochytrium dendrobatidis (Bd). How can a fungal skin infection kill such a broad range of amphibian hosts? And why are certain species particularly susceptible to the impacts of Bd? Here we use a genomics approach to understand the genetic response of multiple susceptible frog species to Bd infection. We characterize the transcriptomes of two closely-related endangered frog species (Rana muscosa and Rana sierrae) and analyze whole genome expression profiles from frogs in controlled Bd-infection experiments. We integrate the Rana results with a comparable dataset from a more distantly-related susceptible species (Silurana tropicalis). We demonstrate that Bd-infected frogs show

ORGANISM(S): Rana sierrae

SUBMITTER: Thomas Poorten 

PROVIDER: E-GEOD-34235 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress