Replication Timing by Repli-seq from ENCODE/University of Washington

ABSTRACT: This track is produced as part of the ENCODE Project. This track shows genome-wide assessment of DNA replication timing in cell lines using the sequencing-based "Repli-seq" methodology (see below). Replication timing is known to be an important feature for epigenetic control of gene expression that usually operates at a higher-order level than at the level of specific genes. For each experiment (cell line, replicate), replication timing was ascertained by the isolation and sequencing of newly replicated DNA from six cell cycle fractions: G1/G1b, S1, S2, S3, S4, G2 (six fraction profile). Replication patterns are visualized as a continuous function based on sequencing tag density (Percentage-normalized Signal) and as a wavelet-smoothed transform of the six fraction profile (Wavele

ORGANISM(S): Homo sapiens

SUBMITTER: UCSC ENCODE DCC 

PROVIDER: E-GEOD-34399 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress