Global profiling of gene expression in the ΔdigR and ΔsgmT mutant of Myxococcus xanthus
Ontology highlight
ABSTRACT:
ORGANISM(S): Myxococcus xanthus
SUBMITTER: Anke Treuner-Lange
PROVIDER: E-GEOD-34408 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
The orphan histidine protein kinase SgmT is a c-di-GMP receptor and regulates composition of the extracellular matrix together with the orphan DNA binding response regulator DigR in Myxococcus xanthus.
Petters Tobias T Zhang Xin X Nesper Jutta J Treuner-Lange Anke A Gomez-Santos Nuria N Hoppert Michael M Jenal Urs U Søgaard-Andersen Lotte L
Molecular microbiology 20120306 1
In Myxococcus xanthus the extracellular matrix is essential for type IV pili-dependent motility and starvation-induced fruiting body formation. Proteins of two-component systems including the orphan DNA binding response regulator DigR are essential in regulating the composition of the extracellular matrix. We identify the orphan hybrid histidine kinase SgmT as the partner kinase of DigR. In addition to kinase and receiver domains, SgmT consists of an N-terminal GAF domain and a C-terminal GGDEF ...[more]
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