Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Genome-wide mRNA profiling for identification of specific body fluid markers


ABSTRACT: Genome-wide expression profiling of four kinds of body fluid samples (blood, saliva, semen and vaginal swab). The purpose of the present study was selection of specific mRNA markers for identification of the four body fluids. Results provide important information about gene expression level of each body fluid for forensic science. Total RNAs isolated from four kinds of body fluid samples (blood, saliva, semen and vaginal swab) obtained from Korean volunteers

ORGANISM(S): Homo sapiens

SUBMITTER: Seon-Young Kim 

PROVIDER: E-GEOD-34844 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Genome-wide mRNA profiling and multiplex quantitative RT-PCR for forensic body fluid identification.

Park Seong-Min SM   Park Seong-Yeon SY   Kim Jeong-Hwan JH   Kang Tae-Wook TW   Park Jong-Lyul JL   Woo Kwang-Man KM   Kim Jong-Sik JS   Lee Han-Chul HC   Kim Seon-Young SY   Lee Seung-Hwan SH  

Forensic science international. Genetics 20120929 1


In forensic science, identifying a tissue where a forensic specimen was originated is one of the principal challenges. Messenger RNA (mRNA) profile clearly reveals tissue-specific gene expression patterns that many attempts have been made to use RNA for forensic tissue identification. To systematically investigate the body-fluid-specific expression of mRNAs and find novel mRNA markers for forensic body fluid identification, we performed DNA microarray experiment with 24 Korean body fluid samples  ...[more]

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