TOXICOLOGY TAILORED LOW DENSITY MICROARRAY FOR THE THICKLIP GREY MULLET Chelon labrosus DEVELOPMENT, PRODUCTION AND VALIDATION

ABSTRACT: The widely distributed thicklip grey mullet (Chelon labrosus) has been proposed as a suitable sentinel of pollution since it is able to survive heavily polluted marine/estuarine waters. Previous studies applying molecular to histological level biomarkers have indicated that mullets respond to exposure to chemical compounds. Microarrays are used to identify gene pathways responsive to specific chemical exposures. In this context, fragments of 129 genes relevant in peroxisome proliferation, detoxification, lipid metabolism, inflammatory/immune response, metal sequestration, oxidative and general stress, cell cycle regulation and proliferation, apoptosis, protein synthesis/degradation, and endocrine disruption were cloned through homological cloning using degenerate primers for microchip crea

ORGANISM(S): Chelon labrosus

SUBMITTER: Ibon Cancio 

PROVIDER: E-GEOD-35054 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress