MicroRNA expression in lineage specific hematopoiesis

ABSTRACT: MicroRNA plays a critical role in a wide variety of biological processes and regulate genes associated with different biological processes such as development, proliferation, apoptosis, stress response, and tumourigenesis. Profiling miRNA expression during differentiation of embryonic stem cells will help to understand the regulation pathway of differentiation, which in turn may elucidate disease mechanisms. In human hematopoiesis that requires a tight control of gene expression, lineage-specific transcription factors have long been known to act as key regulators of gene expression in multiple cell-fate decisions that govern cell differentiation. Given the important role of miRNAs in development and differentiation, it would be beneficial to elucidate the role of miRNAs in hematopoiesis fo

ORGANISM(S): Homo sapiens

SUBMITTER: Jennifer Barb 

PROVIDER: E-GEOD-35532 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress