Gene expression changes associated with prognosis of Merkel cell carcinoma

ABSTRACT: Purpose: Due to the rarity of Merkel Cell Carcinoma (MCC), prospective clinical trials have not been practical. This study seeks to identify biomarkers to differentiate between patients with a good and poor prognosis. Methods: Patients were stratified into good, moderate or poor prognosis. Merkel cell carcinoma (MCC) patients were stratified into one of three groups based upon status 24 months following treatment. Poor prognosis patients either presented with or progressed to distant metastasis. Patients with favorable prognosis had local disease presentation with no subsequent recurrence or nodal disease at presentation with no progression during follow-up of longer than 24 months. Moderate prognosis had recurrent local disease, development of nodal metastasis, or nodal disease at presen

ORGANISM(S): Homo sapiens

SUBMITTER: Bryan Thibodeau 

PROVIDER: E-GEOD-36150 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress